WebSemaphorin 3A is a secreted disulfide-bound homodimer involved in the nervous system in growth cone collapse and axon growth repulsion. Recently, recombinant semaphorin 3A … WebSemaphorin 3A (Sema3A) is a protein identified originally as a diffusible axonal chemorepellent. Sema3A has multifunctional roles in embryonic development, immune …
Human Semaphorin 3A (Sema 3A) ELISA Kit- CUSABIO
WebFeb 28, 2024 · Mutation of SEMA3A in this case was previously identified in a subject with Kallmann syndrome, and cells harboring this gene mutation had impaired signaling activity of the secreted protein semaphoring-3A . This suggests that the point mutation of SEMA3A has a pathogenic effect, which may explain the coexistence of IHH in this subject. WebJan 1, 2014 · Semaphorin 3A (Sema3A) is a protein identified originally as a diffusible axonal chemorepellent. Sema3A has multifunctional roles in embryonic development, immune regulation, vascularization, and oncogenesis. ... a sema domain, plexin semaphoring integrin (PSI) domains, and Ig-like plexin transcription factors (IPT). The … charismatic voice heart
Semaphorin 3A - an overview ScienceDirect Topics
WebHere, we have investigated the role of microR-30c (miR-30c) and its target, semaphoring 3A (sema3A), in regulating adult neurogenesis and mechanisms underlying this process. Materials and methods In situ hybridization, immunofluorescence and quantitative real-time PCR were used to assess complementary expression patterns of miR-30c and sema3A ... The SEMA3A gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted Semaphorin-3A protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, … See more Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene. See more The protein semaphorin-3A is highly expressed in scar tissue after traumatic central nervous system injuries, such as spinal cord injury. Semaphorin-3A, and the other class 3 See more • SEMA3A human gene location in the UCSC Genome Browser. • SEMA3A human gene details in the UCSC Genome Browser. See more • Schmidt EF, Strittmatter SM (2007). "The CRMP family of proteins and their role in Sema3A signaling". Semaphorins: Receptor and Intracellular Signaling Mechanisms See more WebSemaphorins are a large family of proteins originally identified as axon guidance factors of the developing nervous system. Semaphorins act as both repellents and attractants for growing axons and thus have a significant function in central nervous system (CNS) development. Semaphorins may guide growing dendrites as well as axons. charismatic voice singer