Human cop1
WebCOP1 Name Type symbol Gene Model Type protein_coding Aliases AJ000535; AJ000536; L24437 Description Represses photomorphogenesis and induces skotomorphogenesis in the dark. Contains a ring finger zinc-binding motif, a coiled-coil domain, and several WD-40 repeats, similar to G-beta proteins. WebDetection of human COP1/RFWD2 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-COP1/RFWD2 antibody A300-894A (lot A300-894A-2) used for IP at 6 µg per reaction.
Human cop1
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Web15 mei 2011 · COP1 Is a Tumour Suppressor That Causes Degradation of ETS Transcription Factors. The proto-oncogenes ETV1, ETV4 and ETV5 encode transcription … WebCop1 - Solidarités Étudiantes. août 2024 - aujourd’hui9 mois. Ville de Paris, Île-de-France, France. Chargée de l’organisation de collectes au sein de magasins, entreprises, universités et lycées. - Supervision d’une équipe d’une quinzaine de bénévoles. - Prise de contact avec les magasins et autres partenaires.
Web15 okt. 2004 · COP1 is a RING finger-containing protein that targets p53 for degradation to the proteasome and is necessary for p53 turnover in normal and cancer cells. However, the association between COP1 and cancer remains to be determined. We performed expression analysis of COP1 in ovarian and breast cancer tissue microarrays. WebCOP1 is an evolutionarily conserved RING-finger ubiquitin ligase acting within a Cullin-RING ligase (CRL) complex that promotes polyubiquitination of c-Jun and p53. Stability of the above substrates is affected by …
WebCOP1 plays a central role in repressing photomorphogenesis in the dark by forming multiple complexes with SUPPRESSOR OF PHYTOCHROME A-105 (SPA1-4) family members in a tissue- and developmental stage–specific manner ( Deng et al., 1992; Hoecker et al., 1999; Osterlund et al., 2000; Laubinger et al., 2004; Zhu et al., 2008; Lau and Deng, 2012 ). WebThe COP1-mediated degradation of p53 regulates cancer cell growth and apoptosis. Our results indicate that COP1 regulates human breast cancer cell proliferation and …
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Web14 apr. 2024 · Buscamos profesional en carreras administrativas o carrera afin con 2 a 3 años de experiencia en ventas realización de ventas 100%. Perfil con agilidad, prospección de venta, comunicación asertiva, proactivo, manejo de presión y buen manejo de ingles getting help with court feesWebCreated by Human Grunt. yeet NO C_HANDS 3 Models: IAA Black, IAA White and IAA Chinese NPCs will have a random model and random bodygroups I did not make this with the intention of being used for posing and stuff, there isn't even finger posing ... Warning: Cop1 and cop2 models can stay standard ... christopher conrad jorgensenWebCOP1 can play tumor suppressive and oncogenic roles in human malignancies, urging us to summarize the functions of COP1 in tumorigenesis. In this review, we describe the … getting help with credit card debtWeb1 okt. 2002 · Component of the DCX DET1-COP1 ubiquitin ligase complex at least composed of RBX1, DET1, DDB1, CUL4A and COP1. Isoform 2 does not interact with … getting help with childcare costsWeb27 nov. 2024 · Hac1 is a transcription factor that executes the UPR by activating genes involved in ER homeostasis. The UPR, and the mechanism of activation by splicing of a specific mRNA, is conserved from yeast to humans. Mammalian cells have an IRE1 ortholog named ERN1. Likewise, HAC1 has a functional human homolog, XBP1 [ 9 ]. getting help with electric bill in indianaWeb30 mei 2003 · Human COP1 shows a high degree of sequence conservation and domain organization with its plant counterpart. We found that transfected huCOP1 distributed to the cytoplasm and the nucleus of cells and that nuclear localization was directed by a NLS located in the amino-terminal region of the protein. christopher conrad jurgensenWebCOP1 is found not only in plants, but also in vertebrates, where it plays a role in the degradation of transcription factors such as p53 and the c-Jun protein . Interestingly, … christopher conradi