Erk2 molecular weight
WebHighly specific and rigorously validated in-house, p42 MAP Kinase (Erk2) Antibody (CST #9108) is ready to ship. ... Loading of prestained molecular weight markers (#59329, 10 µl/lane) to verify electrotransfer and … WebApr 7, 2024 · A cross-linking experiment in cells overexpressing Flag-ERK2 further revealed that EDI specifically binds to activated but not inactive, unstimulated ERK2, as suggested by the molecular weight/mobility shift of ERK2 after stimulation with carbachol (Supplementary Fig. 5D).
Erk2 molecular weight
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WebFeb 28, 2024 · Specifically, a strong band of 2pERK was detected in mitochondria, which matches the molecular weight of ERK2, indicating a strong differential regulation of ERK2 in mitochondria. Then, H 2 O 2 administration promotes a strong appearance of pTyr signal in mitochondria, suggesting that the translocated pYERK now is double phosphorylated … WebVX-11e (VTX-11e, Vertex-11e) is a potent, selective, and orally bioavailable ERK2 inhibitor with Ki of <2 nM, over 200-fold selective over other kinases tested. CAS No. 896720-20-0 Selleck's VX-11e has been cited by 18 …
WebDec 15, 2006 · The extracellular signal-regulated kinases (ERK1 and ERK2) are important mediators of cell proliferation. Constitutive activation of the ERK proteins plays a critical role in the proliferation of many human cancers. ... (CADD) to identify novel low molecular weight compounds that interact with ERK2 in an ATP-independent manner and disrupt ... WebCalculated molecular weight: 360 aa, 41 kDa: Observed molecular weight: 38-44 kDa: GenBank accession number: BC017832: Gene symbol: …
WebDec 7, 2016 · Mix ERK2 and PEA-15 (1:1 molar ratio) and concentrate to ~2 mL using a centrifugal concentrator (5 kDa molecular weight cutoff). 2. This material is loaded (0.5 mL/min) onto a Superdex-200 size-exclusion chromatography column equilibrated in size-exclusion chromatography buffer. WebProduct Specific Information This antibody detects endogenous protein at a molecular weight of 42 and 44 kDa. Purity is >95% by SDS-PAGE. Target Information ERK1 and ERK2 are widely expressed and are involved in …
Webp44/42 MAPK (Erk1/2) Antibody detects endogenous levels of total p44/42 MAP kinase (Erk1/Erk2) protein. In some cell types, this antibody …
WebJan 15, 2024 · ERK1 and ERK2 are two important members of the MAPK/ERK pathway, with molecular weights of 44 and 42 kDa, respectively ( 33 ). The C-terminus of ERK5 contains a nuclear … ffalcon 50uf1 50 4k ultra hd led smart tvWebPhospho-ERK1/ERK2 (Thr202, Tyr204) Antibody (36-8800) in ICC/IF Immunofluorescent analysis of Phospho-p44 MAPK + p42 MAPK pThr202 + pTyr204 Antibody was done on 70% confluent log phase A549 cells. denbighshire children\\u0027s social servicesWebKey features and details Rabbit polyclonal to ERK1 + ERK2 Suitable for: ICC, IHC-P, WB Reacts with: Mouse, Rat, Human Isotype: IgG Get better batch-to-batch reproducibility … ffalcon ms6586WebNational Center for Biotechnology Information denbighshire climate emergencyWebIn rodents, for example mouse ERK1b has a smaller molecular weight than mouse ERK1 (−0.67 kD) while rat ERK1b has a larger molecular weight than rat ERK1 (+2.66 kD). … ffalcon ms6586 software updateWebMay 27, 2024 · The liver weight is similar between WT and Erk2−/−mice. However, the body weight in Erk2−/−mice is slightly lower than WT mice. Therefore, the percentages of liver weight to body weight in Erk2−/−mice were higher than those of WT mice (Figure 1b). The percentages of α-SMA in KO liver sections were similar to that in WT sections. denbighshire cleanersWebERK1/2 are proline-directed kinases that preferentially catalyze the phosphorylation of substrates containing a Pro-Xxx-Ser/Thr-Pro sequence. Besides this primary structure … ffalcon 55uf2 55 ultra hd hdr smart tv