WebAug 2, 2024 · Beta blockers such as metoprolol have been associated with weight gain ranging from insignificant to almost 10 pounds after a year of treatment. Most of the weight gain tends to occur in the first few months. WebMetoprolol is not likely to cause weight gain. However, weight gain can be a warning sign that heart failure is getting worse. If you are taking metoprolol for heart failure, tell your doctor right away if you gain weight suddenly. This weight gain is due to extra fluid in the body that may cause swelling in the feet, ankles, legs and belly.
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